Peroxide oxidation of lipids and antioxidant protection of an organism of cows during dry period at impact of antibiotic of prolonged action

Abstract

The purpose. To study effect of antibiotic of prolonged action Oksiprol on processes of peroxide oxidation of lipids and activity of ferments of antioxidant systems of blood of cows during dry period. Methods. Biochemical, photometric, statistical. To cows of experimental group 30 day prior to calving intramuscularly inducted a specimen Oksiprol in dose of 1 cm3 for 10 kg of mass of a body. Results. After application of Oksiprol during dry period the content of diene conjugates in blood serum drops for 28,47% (P<=0,01), of malonic dial — for 12,5% (P<=0,05), while catalase activity increases for 36,47% (P<=0,01), and density of hepatocuprein — for 30,55% (P<=0,01) in comparison with the beginning of experiment, on the background of uncertain fluctuation of the content of these indexes in blood of cows of control group. Conclusions. Application of Oksiprol in dry period makes active enzymatic link of antioxidant protection of an organism, slows down activity of processes of peroxide oxidation of lipids, which prevent development of morbid conditions. With the purpose of prophylactics of development of morbid conditions at cows it is recommended